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Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against ...
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Sep 7, 2023 · MT-TRX has a role in the regulation of the mitochondrial membrane potential and cell death. mitochondrial thioredoxin may play important roles in protection against oxidant-induced apoptosis. Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha. This nuclear gene encodes a mitochondrial member of ...
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Furthermore, the Deltatzn1 mutant was found to have severely reduced zinc content indicating that tzn1 functions as a key regulator of intracellular zinc levels in Neurospora crassa. Zinc uptake studies indicate tzn1 is a specific transporter of zinc, while tzn2 transports both zinc and cadmium. Quantitative RT-PCR showed up-regulation of tzn1 ...uwatchfree.ax (hosted on gigenet.com) details, including IP, backlinks, redirect information, and reverse IP shared hosting data
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